Covid-19 anniversary: How have GSK and Astrazeneca fared since?

It’s been four years since the UK went into its first Covid-19 lockdown. Since then, the world has changed dramatically. The investment landscape has also changed dramatically.

The pandemic upended traditional working practices, and investors were quick to take note.

They sold holdings in real estate investment trusts with exposure to offices while buying tech stocks with exposure to the changing landscape of work.

The Covid-19 pandemic also ignited interest in the pharmaceutical sector. Even before the UK went into lockdown, the sector was looking for ways to fight the virus.

From vaccines to build immunity to the virus to drugs that would help victims fight off the infection in hospitals, the sector had a key role.

The UK’s leading pharmaceutical companies, GSK and Astrazeneca, both played a role in the battle against Covid-19, but how have they fared since?

Astrazeneca led the fight against the virus with its vaccine, developed in conjunction with Oxford scientists. Within a year of successful trials, the company had delivered 2bn doses of the treatment.

At the same time, the group was spending heavily on its oncology portfolio. It has bought several companies, the biggest of which was Alexion Pharmaceuticals in the US.

The new treatments acquired and developed will bring in billions of pounds in revenue for the group over the next few years, and it does not look as if the business will stop growing anytime soon, which should support earnings and dividend growth in the years ahead.

As Steve Clayton, head of equity funds at Hargreaves Lansdown noted: “This combination of developing their own research pipeline and then buying and selling smaller companies or development candidates from their existing portfolio has been a particular feature at Astrazeneca.

Vials labelled “AstraZeneca COVID-19 Coronavirus Vaccine” and a syringe are seen in front of a displayed AstraZeneca logo in this illustration taken March 10, 2021. REUTERS/Dado Ruvic/Illustration/File Photo

“Managing their portfolio in this way helped the group to maintain and grow its dividend, until the cash flows from its major new cancer drugs had built up. This commitment to the dividend has been in contrast to GSK, who have recently cut their payout to shareholders,” Clayton added.

“Along the way it has grown its revenues by almost 100% in the last decade, with profits nearly doubling. Shareholders have done well, too. Dividends have been held or grown every year and the share price has more than doubled in ten years.”

At the other end of the spectrum, GSK has been focused on developing new medicines and vaccines.

These have yet to pay off, but the company has reported a pipeline of 71 assets is predicted by GSK to contain at least 12 major new products to be launched from 2025 onwards.

Despite their efforts to grow post Covid-19, both GSK and Astrazeneca have missed one of the biggest opportunities in the pharma sector in recent years—weight loss drugs.

Novo Nordisk of Denmark has grown to be Europe’s most valuable company due to the successes of weight loss drugs Ozempic and Wegovy.

While new products could take up to a decade to develop, GSK and Astrazeneca could decide to get involved. Even if they don’t, its been a long time since the sector looked so attractive.

As Steve Clayton explained: “We expect there will be a scramble by the big pharmaceuticals firms to acquire smaller rivals with promising GLP-1 [weight loss drugs] candidates under development as they try to catch up.

“With robust cash flows coming from their existing portfolios AZN and GSK have the firepower to get involved if they see the right opportunity. It’s been a long time since the pharmaceutical sector looked so interesting and the only certainty is that there will be changes ahead.”

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